How Is Proximity Labeling Technology Creating New Epitope Tag...

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2026-05-14 10:09:49

How Is Proximity Labeling Technology Creating New Epitope Tag Applications

Proximity labeling epitope tag technology — the fusion of promiscuous biotin ligase enzymes (BirA*, TurboID, miniTurbo) or ascorbate peroxidase (APEX2) to proteins of interest enabling biotinylation of proximal proteins within a defined radius (approximately ten nanometers) in living cells, followed by streptavidin-based capture and mass spectrometric identification of the biotinylated...

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