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Beyond Nature's Limits: Why Modern Glycoprotein Synthesis Solves the Heterogeneity Problem
Glycoproteins govern everything from cell-cell communication to pathogen recognition, yet most researchers unknowingly work with a messy reality. When isolated from natural sources, these complex molecules exist as heterogeneous mixtures of related glycoforms—identical protein backbones carrying different sugar structures. Nature provides no proofreading mechanism to correct this...
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